IMPACT OF LIPID-BASED NUTRITIONAL SUPPLEMENTATION IN PRIMI-GRAVIDAS AND ITS EFFECT ON MATERNAL, BIRTH AND INFANT OUTCOMES: A RANDOMIZED CONTROLLED TRIAL

OBJECTIVE: To find out the effect of Lipid based nutritional supplement (LNS) on body composition, hematological findings, maternal, birth and infant outcomes in underweight primi-gravidas. METHODS: This single-blinded randomized controlled clinical trial was executed tertiary care hospitals Khyber Pakhtunkhwa province, Pakistan from April 2018 to August 2019. Forty primi-gravidas recruited study were into LNS placebo groups. group received 75 gms high energy supplement, named “MAAMTA”, daily basis their first antenatal visit till delivery addition conventional treatment. Fasting blood samples taken composition measured at baseline visit, 16th week gestation post-natally. For measurement parameters neonates cord obtained. Data 36 participants (LNS n=19; n=17) available for final analysis. RESULTS: Majority (n=33/36; 91.7%) had normal vaginal deliveries (n=18/19 & n=15/17 group). Frequency Cesarean section 1/19 (5.3%) 2/17 (11.8%) group. No case abortion reported. Mean crown heel length (CHL) 47.11±2.747 cm 44.24±2.359 (p=0.002). fronto-occipital circumference 35.11±1.663 32.41±7.859 groups respectively (p=0.153). difference observed between maternal gestational weight gain per prevalence anemia, mortality neonatal weight. CONCLUSION: The prenatal use increases CHL